Invitrogen™ CRTAC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552525

Catalog No. PIPA552525

Description

Immunogen sequence: VVTDFDGDGM LDLILSHGES MAQPLSVFRG NQGFNNNWLR VVPRTRFGAF ARGAKVVLYT KKSGAHLRII DGGSGYLCEM EPVAHFGLGK DEASSVEVTW PDGKMVSRNV ASGEMNSVLE ILYPRDEDTL QDPAP Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 93%.

CRTAC1 encodes a glycosylated extracellular matrix protein that is found in the interterritorial matrix of articular deep zone cartilage. This protein is used as a marker to distinguish chondrocytes from osteoblasts and mesenchymal stem cells in culture. The presence of FG-GAP motifs and an RGD integrin-binding motif suggests that this protein may be involved in cell-cell or cell-matrix interactions. Copy number alterations in this gene have been observed in neurofibromatosis type 1-associated glomus tumors. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: CRTAC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CRTAC1
• Gene Alias: 2810454P21Rik; 68 kDa chondrocyte-expressed protein; acidic secreted protein in cartilage; ASPIC; ASPIC1; AW047536; cartilage acidic protein 1; Cep68; CEP-68; chondrocyte expressed protein 68 kDa CEP-68; Crtac1; Crtac1B; FLJ10320; Lotus; Protein CRTAC1-B; W307
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55118
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NQ79
• Gene Symbols: CRTAC1
• Immunogen: Recombinant protein corresponding to Human CRTAC1. Recombinant protein control fragment (Product #RP-89891).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG