Invitrogen™ CRTAM Monoclonal Antibody (06)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA530277

Catalog No. PIMA530277

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human CRTAM.

Class-I MHC-restricted T cell-associated molecule (CRTAM) is a gene located on chromosome 11q24.2, encoding a member of the immunoglobulin superfamily that plays a crucial role in immune cell interactions. CRTAM is expressed on activated CD8+ T cells, natural killer (NK) cells, and some subsets of CD4+ T cells, where it is involved in promoting cell adhesion, cytokine production, and cytotoxic responses. The protein binds to Necl-2 (CD112), mediating intercellular communication that influences immune responses, particularly in the context of viral infections and tumor surveillance. CRTAM's involvement in directing immune cell activity highlights its importance in the regulation of adaptive and innate immunity. Research into CRTAM is exploring its potential as a therapeutic target for modulating immune functions, aiming to enhance immune responses against cancer and infectious diseases or to attenuate autoimmune reactions.

Specifications

• Antigen: CRTAM
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O95727
• Gene Symbols: CRTAM
• Immunogen: Recombinant Human CRTAM Protein (Met1-Ser286).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: 06
• Conjugate: Unconjugated
• Gene: CRTAM
• Gene Alias: CD355; CD355 antigen; class I MHC restricted T cell associated molecule; class I-restricted T cell-associated molecule; class-I MHC-restricted T cell associated molecule; class-I MHC-restricted T-cell-associated molecule; Crtam; cytotoxic and regulatory T cell molecule; cytotoxic and regulatory T-cell molecule
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 56253
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid