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Invitrogen™ CRTAM Monoclonal Antibody (06)
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Catalog No. PIMA530277
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100 μL
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Catalog No. Quantity
PIMA530277 100 μL
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Catalog No. PIMA530277 Supplier Invitrogen™ Supplier No. MA530277
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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human CRTAM.

Class-I MHC-restricted T cell-associated molecule (CRTAM) is a gene located on chromosome 11q24.2, encoding a member of the immunoglobulin superfamily that plays a crucial role in immune cell interactions. CRTAM is expressed on activated CD8+ T cells, natural killer (NK) cells, and some subsets of CD4+ T cells, where it is involved in promoting cell adhesion, cytokine production, and cytotoxic responses. The protein binds to Necl-2 (CD112), mediating intercellular communication that influences immune responses, particularly in the context of viral infections and tumor surveillance. CRTAM's involvement in directing immune cell activity highlights its importance in the regulation of adaptive and innate immunity. Research into CRTAM is exploring its potential as a therapeutic target for modulating immune functions, aiming to enhance immune responses against cancer and infectious diseases or to attenuate autoimmune reactions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CRTAM
Applications ELISA
Classification Monoclonal
Clone 06
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CRTAM
Gene Accession No. O95727
Gene Alias CD355; CD355 antigen; class I MHC restricted T cell associated molecule; class I-restricted T cell-associated molecule; class-I MHC-restricted T cell associated molecule; class-I MHC-restricted T-cell-associated molecule; Crtam; cytotoxic and regulatory T cell molecule; cytotoxic and regulatory T-cell molecule
Gene Symbols CRTAM
Host Species Mouse
Immunogen Recombinant Human CRTAM Protein (Met1-Ser286).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56253
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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