Invitrogen™ CRYBA2 Polyclonal Antibody

Catalog No.	Quantity
PIPA584545	100 μL

Catalog No. PIPA584545 Supplier Invitrogen™ Supplier No. PA584545

Description

Rabbit Polyclonal Antibody

Immunogen sequence: GYQYVLERDR HSGEFCTYGE LGTQAHTGQL QSIRRVQH Highest antigen sequence indentity to the following orthologs: Mouse - 89%, Rat - 89%.

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of the vertebrate eye, which function to maintain the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also defined as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group but absent in the acidic group). Beta-crystallins form aggregates of different sizes and are able to form homodimers through self-association or heterodimers with other beta-crystallins. This gene is a beta acidic group member. Three alternatively spliced transcript variants encoding identical proteins have been reported.

Specifications

• Antigen: CRYBA2
• Applications: Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 0.1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: Cryba2
• Gene Accession No.: P53672
• Gene Alias: beta-A2 crystallin; betaA2-crystallin; Beta-crystallin A2; Cryba2; crystallin beta A2; crystallin, beta A2; CTRCT42; E130107M19Rik; eye lens structural protein; lens structural protein
• Gene Symbols: Cryba2
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human CRYBA2. Recombinant protein control fragment (Product #RP-108468).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1412
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG