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Invitrogen™ CRYGD Polyclonal Antibody
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Catalog No. PIPA583543
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PIPA583543 100 μL
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Catalog No. PIPA583543 Supplier Invitrogen™ Supplier No. PA583543
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Rabbit Polyclonal Antibody

Immunogen sequence: REDYRGQMIE FTEDCSCLQD RFRFNEI Highest antigen sequence indentity to the following orthologs: Mouse - 85%, Rat - 85%.

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CRYGD
Applications Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CRYGD
Gene Accession No. P07320
Gene Alias Aey4; Beta4abc; CACA; CCA3; CCP; Cryg-1; Cryg4; Crygd; cry-g-D; crystallin gamma D; crystallin, gamma D; Crystallin, gamma polypeptide 4; CTRCT4; DGcry-1; gamma crystallin 4; Gamma crystallin D; Gamma D crystallin; gamma-crystallin 1; Gamma-crystallin 2-2; gamma-crystallin 4; Gamma-crystallin D; gamma-D-crystallin; Len; lens opacity 12; Lop12; PCC
Gene Symbols CRYGD
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CRYGD. Recombinant protein control fragment (Product #RP-108353).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1421
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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