Invitrogen™ CSH1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560480

Catalog No. PIPA560480

Description

Immunogen sequence: SHNHDALLKN YGLLYCFRKD MDKVETFLRM VQCRSVEGSC GF Highest antigen sequence identity to the following orthologs: Mouse - 60%, Rat - 58%.

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.

Specifications

• Antigen: CSH1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CSH1
• Gene Alias: Choriomammotropin; chorionic somatomammotropin A; chorionic somatomammotropin hormone 1; chorionic somatomammotropin hormone 1 (placental lactogen); Chorionic somatomammotropin hormone 2; chorionic somatomammotropin-1; CS-1; CSA; CSH1; CSH2; CSMT; GHB3; growth hormone B3; hCS-1; hCS-A; hPL; Lactogen; PL; placental lactogen
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1442
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P0DML2
• Gene Symbols: CSH1
• Immunogen: Recombinant protein corresponding to Human CSH1. Recombinant protein control fragment (Product #RP-104361).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG