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Invitrogen™ CSNK1A1L Polyclonal Antibody
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Catalog No. PIPA5113206
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100 μL
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PIPA5113206 100 μL
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Catalog No. PIPA5113206 Supplier Invitrogen™ Supplier No. PA5113206
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Rabbit Polyclonal Antibody

CSNK1A1L Polyclonal Antibody for Western Blot, IHC (P), ELISA

CSNK1A1L serine/threonine kinase or CK1-alpha dynamically associates with the CBM complex upon T cell receptor engagement to participate in cytokine production and lymphocyte proliferation which has a contrasting role by subsequently promoting the phosphorylation and inactivation of CARMA1. It governs antigen-receptor-induced NF-kappa-B activation and human lymphoma cell survival. These kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins including CTNNB1, PER1, and PER2. CSNK1A1 also participates in Wnt signaling.It may play a role in segregating chromosomes during mitosis, as well as, cytoskeleton diassembly which may regulate epithelial cell migration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CSNK1A1L
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.45 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CSNK1A1L
Gene Accession No. Q8N752
Gene Alias casein kinase 1 alpha 1 like; casein kinase 1, alpha 1-like; casein kinase I alpha S-like; casein kinase I isoform alpha-like; CK1; CKI-alpha-like; CSNK1A1L
Gene Symbols CSNK1A1L
Host Species Rabbit
Immunogen Recombinant Human Casein kinase I isoform alpha-like protein (1-337AA).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 122011
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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