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Invitrogen™ CST1 Monoclonal Antibody (17)
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Catalog No. PIMA530289
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PIMA530289 100 μL
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Catalog No. PIMA530289 Supplier Invitrogen™ Supplier No. MA530289
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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Cystatin SN/CST1.

The cystatin superfamily is a well-established family of cysteine protease inhibitors. Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN and SA cystatins are extracellular (type 2); and the kininogens are type 3 cystatins which are intravascular proteins. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes. Cystatin SA, cystatin S and cystatin SN are found primarily in saliva. Cystatin S and SN can also be expressed in tears, urine and seminal fluid. Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens. Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins. The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation. High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CST1
Applications ELISA
Classification Monoclonal
Clone 17
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene CST1
Gene Accession No. P01037
Gene Alias 1810034E21Rik; alcadein alpha; alcadein-alpha; alc-alpha; calsyntenin 1; calsyntenin-1; Clstn1; Cs1; CST1; Cst-1; Cstn1; C-terminal fragment 1-alpha; CTF1-alpha; Cystain-SA-I; cystatin 1; cystatin SA-I; cystatin SN; cystatin-1; Cystatin-SN; cysteine proteinase inhibitor, type 2 family; Kiaa0911; SAlc-alpha; Salivary cystatin-SA-1; Soluble Alc-alpha
Gene Symbols CST1
Host Species Mouse
Immunogen Recombinant Human Cystatin SN/CST1 Protein (Met1-Ser141).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1469
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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