Invitrogen™ CST1 Monoclonal Antibody (17)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA530289

Catalog No. PIMA530289

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human Cystatin SN/CST1.

The cystatin superfamily is a well-established family of cysteine protease inhibitors. Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN and SA cystatins are extracellular (type 2); and the kininogens are type 3 cystatins which are intravascular proteins. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes. Cystatin SA, cystatin S and cystatin SN are found primarily in saliva. Cystatin S and SN can also be expressed in tears, urine and seminal fluid. Cystatin C is a related protein which is expressed in brain, thymus, ovary, epididymis and vas deferens. Cystatin D protects against proteinases in the oral cavity, while Cystatin E/M and F moderate the inhibition of cathepsin proteins. The fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis and bone resorption, regulation of the insulin and hepatocyte growth factor receptors and the response to systemic inflammation. High molecular weight kininogen (Kininogen HC) and low molecular weight kininogen (Kininogen LC) have varied roles, though they both inhibit the thrombin- and plasmin-induced aggregation of thrombocytes.

Specifications

• Antigen: CST1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P01037
• Gene Symbols: CST1
• Immunogen: Recombinant Human Cystatin SN/CST1 Protein (Met1-Ser141).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: 17
• Conjugate: Unconjugated
• Gene: CST1
• Gene Alias: 1810034E21Rik; alcadein alpha; alcadein-alpha; alc-alpha; calsyntenin 1; calsyntenin-1; Clstn1; Cs1; CST1; Cst-1; Cstn1; C-terminal fragment 1-alpha; CTF1-alpha; Cystain-SA-I; cystatin 1; cystatin SA-I; cystatin SN; cystatin-1; Cystatin-SN; cysteine proteinase inhibitor, type 2 family; Kiaa0911; SAlc-alpha; Salivary cystatin-SA-1; Soluble Alc-alpha
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1469
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid