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CTCF Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501571390
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50-157-1390 10 μL
50-157-1389 100 μL
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Catalog No. 50-157-1390 Supplier Bethyl Laboratories, Inc Supplier No. IHC00046T
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Pig, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon an

This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms′ tumors.Tissue specificity: Ubiquitous. Absent in primary spermatocytes.

Specifications

Antigen CTCF
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene CTCF
Gene Accession No. P49711
Gene Alias CTCF
Gene Symbols CTCF
Host Species Rabbit
Immunogen Between 650 and 700
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10664
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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