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Invitrogen™ CTDSPL Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA561713
Description
Immunogen sequence: AIITQVTNPK EDEGRLPGAG EKASQCNVSL KKQRSRSILS SFFCCFRDYN VEAPPPSSPS VLPPLVEENG GLQKGDQ Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 41%.
Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. [UniProt].
Specifications
CTDSPL | |
Polyclonal | |
Unconjugated | |
CTDSPL | |
2810418J22Rik; AI426263; C3orf8; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 3; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like; CTD small phosphatase like; CTD small phosphatase-like protein; CTDSPL; CTDSP-like; hYA22; MGC71888; Nif1; Nifl; NIF-like protein; NLI-interacting factor 1; nuclear LIM interactor-interacting factor 1; Protein YA22; PSR1; RB protein serine phosphatase from chromosome 3; RBSP3; SCP3; SCP-3; SCP3 COR1; small CTD phosphatase 3; Small C-terminal domain phosphatase 3; YA22 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
10217 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Immunocytochemistry | |
0.2 mg/mL | |
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
O15194 | |
CTDSPL | |
Recombinant protein corresponding to Human CTDSPL. Recombinant protein control fragment (Product #RP-100963). | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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