Invitrogen™ CTH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120971

Catalog No. PIPA5120971

Description

Positive test controls include: HepG2, HeLa, Mouse liver, Mouse kidney. The target is usually found in the following locations: Cytoplasm. Immunogen sequence: MQEKDASSQG FLPHFQHFAT QAIHVGQDPE QWTSRAVVPP ISLSTTFKQG APGQHSGFEY SRSGNPTRNC LEKAVAALDG AKYCLAFASG LAATVTITHL LKAGDQIICM DDVYGGTNRY FRQVASEFGL KISFVDCSKI KLLEAAITPE TKLVWIETPT NPTQKVIDIE GCAHIVHKHG DIILVVDNTF MSPYFQRPLA LGADISMYSA TKYMNGHSDV VMGLVSVNCE SLHNRLRFLQ NSLGAVPSPI DCYLCNRGLK TLHVRMEKHF KNGMAVAQFL ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK NLKLFTLAES LGGFESLAEL PAIMTHASVL KNDRDVLGIS DTLIRLSVGL EDEEDLLEDL DQALKAAHPP SGSHS.

This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Specifications

• Antigen: CTH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CTH
• Gene Alias: 0610010I13Rik; AI314617; BC019483; CSE; Cth; cth protein; CTL target antigen; Cys3; cystathionase; cystathionase (cystathionine gamma-lyase); cystathionase isoform 1; cystathionine gamma-lyase; Cystathionine gamma-lyase-like protein; cysteine desulfhydrase; cysteine-protein sulfhydrase; EGK_00877; fb58d08; gamma-cystathionase; H; homoserine deaminase; homoserine dehydratase; LOC102117863; MGC9471; PRB-RA; probasin-related antigen; QccE-22305; synthase; Unknown (protein for MGC:85785); wu:fb48e03; wu:fb58d08; zgc:66001; zgc:85785
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 107869, 1491, 24962
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.412 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P18757, P32929, Q8VCN5
• Gene Symbols: CTH
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-405 of human Cystathionase/Cystathionase/CTH (NP_0018932).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG