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Invitrogen™ CTHRC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA538054

Catalog No. PIPA538054


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Description

Description

A recommended positive control is rat small intestine tissue lysate. At least two isoforms of CTHRC1 are known to exist; this antibody will detect only the larger isoform.

The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration. CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CTHRC1
Polyclonal
Unconjugated
Cthrc1
1110014B07Rik; collagen triple helix repeat containing 1; collagen triple helix repeat-containing protein 1; CTHRC1; Protein NMTC1; UNQ762/PRO1550
Rabbit
Antigen affinity chromatography
RUO
115908, 282836, 68588
Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q8CG08, Q96CG8, Q9D1D6
Cthrc1
19 amino acid peptide near the amino terminus of human CTHRC1.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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