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CTHRC1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501731013 Shop All Proteintech Group Inc Products
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50-173-1013 150 μL
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Catalog No. 50-173-1013 Supplier Proteintech Group Inc Supplier No. 165341AP150UL
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Rabbit Polyclonal Antibody

The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration. CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells. CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma.

Specifications

Antigen CTHRC1
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.21 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CTHRC1
Gene Accession No. Q8CG08, Q96CG8, Q9D1D6
Gene Alias CTHRC1, Protein NMTC1
Gene Symbols Cthrc1
Host Species Rabbit
Immunogen CTHRC1 Fusion Protein Ag9812
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 115908, 282836, 68588
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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