Invitrogen™ CTLA-4 Monoclonal Antibody (1B8), PE

Armenian Hamster Monoclonal Antibody

Supplier:  Invitrogen™ HMCD15204

Catalog No. 50-113-7436

Description

CTLA-4 Monoclonal Antibody for Flow, ELISA

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.

Specifications

• Antigen: CTLA-4
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with <0.1% sodium azide; pH 7.5
• Gene Accession No.: P09793
• Gene Symbols: CTLA4
• Immunogen: Mouse CD152 (CTLA-4). from Extracellular portion of murine CTLA-4 fused to a murine IgG2a.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry
• Clone: 1B8
• Conjugate: PE
• Gene: CTLA4
• Gene Alias: ALPS5; CD; CD152; CD152 antigen; CD152 isoform; CD152 protein; CD152 protein precursor; celiac disease 3; CELIAC3; Ctla4; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte associated protein 4; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; EGK_04712; GRD4; GSE; ICOS; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; Ly-56; sCTLA4; soluble form; transmembrane form
• Host Species: Armenian Hamster
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 12477
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov