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  6. Invitrogen™ CTLA-4 Monoclonal Antibody (D13), Invitrogen™

Invitrogen™ CTLA-4 Monoclonal Antibody (D13), Invitrogen™
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Catalog No. FEMA551061
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200 μL
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FEMA551061 200 μL
FEMA551062 20 μL
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Catalog No. FEMA551061 Supplier Invitrogen™ Supplier No. MA551061
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Description

Mouse Monoclonal Antibody

CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
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Specifications

Antigen CTLA-4
Applications Western Blot, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone D13
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene CTLA4
Gene Accession No. P16410, Q9MYX7
Gene Alias ALPS5; CD; CD152; CD152 antigen; CD152 isoform; CD152 protein; CD152 protein precursor; celiac disease 3; CELIAC3; Ctla4; CTLA-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte associated protein 4; cytotoxic T-lymphocyte protein 4; cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM; cytotoxic T-lymphocyte-associated antigen 4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte-associated serine esterase-4; EGK_04712; GRD4; GSE; ICOS; IDDM12; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; Ly-56; sCTLA4; soluble form; transmembrane form
Gene Symbols CTLA4
Host Species Mouse
Immunogen Recombinant Human CTLA4 protein, Gly52-Cys211 (Accession #P16410).
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1493, 397286
Target Species Human, Pig
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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