Invitrogen™ CTRL Recombinant Rabbit Monoclonal Antibody (10Z4K3)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537944

Catalog No. PIMA537944

Description

Positive Samples: Mouse pancreas, Rat pancreas Immunogen sequence: GVGNVTPAHL QQVALPLVTV NQCRQYWGSS ITDSMICAGG AGASSCQGDS GGPLVCQKGN TWVLIGIVSW GTKNCNVRAP AVYTRVSKFS TWINQVIAYN.

The CTRL gene encodes chymotrypsin-like protein, a serine protease involved in the digestion of proteins by cleaving peptide bonds. It belongs to the chymotrypsin family of enzymes that are predominantly expressed in the pancreas and play crucial roles in the breakdown of dietary proteins in the small intestine. CTRL functions by hydrolyzing specific peptide bonds, contributing to efficient protein digestion and nutrient absorption. This enzyme's activity is tightly regulated to prevent premature activation within the pancreas, which could lead to pancreatitis or other digestive disorders. The study of the CTRL gene is significant in understanding the mechanisms of digestive health and in diagnosing pancreatic disorders. Furthermore, CTRL's enzyme activity and its role in proteolytic pathways make it an important target for research in digestive enzyme supplementation therapies and treatment strategies for conditions involving impaired protein digestion.

Specifications

• Antigen: CTRL
• Classification: Recombinant Monoclonal
• Concentration: 0.3 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P40313
• Gene Symbols: Ctrl
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 165-264 of human CTRL (P40313).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 10Z4K3
• Conjugate: Unconjugated
• Gene: Ctrl
• Gene Alias: 0910001G08Rik; 1810004D15Rik; AV005227; chymopasin; chymotrypsin A CTRA-1; chymotrypsin like; chymotrypsin-like; chymotrypsin-like protease CTRL-1; Ctra1; Ctra-1; CTRL; CTRL1; mFLJ00366
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 109660, 117184, 1506
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid