CTRP1 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-7806	100 μL

Catalog No. 50-198-7806 Supplier Bioss Supplier No. BS7528R

Description

Rabbit Polyclonal Antibody

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.

Specifications

• Antigen: CTRP1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: C1QTNF1
• Gene Accession No.: Q9BXJ1
• Gene Alias: 1600017K21Rik; C1q and tumor necrosis factor related protein 1; C1QTNF1; Complement C1q tumor necrosis factor-related protein 1; CTRP1; G protein coupled receptor interacting protein; G protein-coupled receptor-interacting protein; GIP; Putative secreted protein ZSIG37; UNQ310/PRO353; Zsig37
• Gene Symbols: C1QTNF1
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human CTRP1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 114897
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG