Invitrogen™ CTRP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558464

Catalog No. PIPA558464

Description

Immunogen sequence: ECSVPPRSAF SAKRSESRVP PPSDAPLPFD RVLVNEQGHY DAVTGKFTCQ V Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 92%.

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.

Specifications

• Antigen: CTRP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C1QTNF5
• Gene Alias: C1q and tumor necrosis factor related protein 5; C1q TNF-alpha-related protein 5; C1qtnf5; Complement C1q tumor necrosis factor-related protein 5; Ctrp5; LORD; Membrane frizzled-related protein; Membrane-type frizzled-related protein; Mfrp; myonectin; UNQ303/PRO344
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114902
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BXJ0
• Gene Symbols: C1QTNF5
• Immunogen: Recombinant protein corresponding to Human CTRP5. Recombinant protein control fragment (Product #RP-97566).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG