Invitrogen™ CTRP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110379

Catalog No. PIPA5110379

Description

Immunogen sequence: SPPLDDNKIP SLCPGHPGLP GTPGHHGSQG LPGRDGRDGR DGAPGAPGEK GEGGRPGLPG PRGDPGPRGE AGPAGPTGPA GECSVPPRSA FSAKRSESRV PPPSDAPLPF DRVLVNEQGH YDAVTGKFTC QVPGVYYFAV HATVYRASLQ FDLVKNGESI ASFFQFFGGW PKPASLSGGA MVRLEPEDQV WVQVGVGDYI GIYASIKTDS TFSGFLVYSD WHSSPVFA.

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.

Specifications

• Antigen: CTRP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C1QTNF5
• Gene Alias: C1q and tumor necrosis factor related protein 5; C1q TNF-alpha-related protein 5; C1qtnf5; Complement C1q tumor necrosis factor-related protein 5; Ctrp5; LORD; Membrane frizzled-related protein; Membrane-type frizzled-related protein; Mfrp; myonectin; UNQ303/PRO344
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114902, 235312, 315598
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.29 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q5FVH0, Q8K479, Q9BXJ0
• Gene Symbols: C1QTNF5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 16-243 of human C1QTNF5 (NP_056460.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG