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Gibco™ CTS™ TrueCut™ Cas9 Protein

Gibco™ CTS TrueCut Cas9 Protein is our highest performing CRISPR-Cas9 protein, engineered to deliver maximum ribonucleoprotein (RNP)-editing efficiency.

$12040.00 - $23070.00

Specifications

Concentration 10 mg/mL
Product Type Cas9 Protein
Shipping Condition Dry Ice
Research Category Genome Editing
Product Line TrueCut™
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
A45220
Encompass
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Gibco™
A45220
2.5 mg
Each for $12,040.00
Add to cart
 
A45221
Encompass
View Documents
Gibco™
A45221
5.0 mg
Each for $23,070.00
Add to cart
 
Description

Description

  • A Streptococcus pyogenes Cas9 (wt) protein, produced by recombinant DNA technology in E. coli for genome editing with CRISPR technology
  • Cas9 protein forms a very stable RNP complex with the guide RNA (gRNA) component of the CRISPR/Cas9 system
  • Incorporation of NLS aids delivery to the nucleus, increasing the editing efficiency and on-target cleavage.
  • Engineered to deliver maximum ribonucleoprotein (RNP)-editing efficiency
  • Manufactured in compliance with standards for Ancillary Materials for Cell, Gene and Tissue-Based Products and is subjected to stringent quality specifications
  • Provided in a high-concentration and large-scale format for process development and clinical research applications

Additional features of CTS TrueCut Cas9 Protein include:

  • Consistent high editing efficiency—superior CRISPR-Cas9 editing efficiency in all tested cell lines including primary immune cells (>90% editing in primary T cells)
  • Higher stringency manufacturing—manufactured to meet the standards for Ancillary Materials for Cell, Gene, and Tissue-Based Products including USP <1043>, Ph.Eur. 5.2.12, and ISO 20399 -1, -2, -3, following the principles of 21 CFR Part 820 in a FDA-registered manufacturing site
  • Aseptic manufacturing—entire process completed using single-use technology
  • Extensive safety testing—includes sterility, endotoxin, mycoplasma, residual nucleic acids, and proteins
  • Sterile filling—finished product is vialed in a Class A/B (Class 100 and ISO 5 equivalents) cleanroom
  • Traceability documentation—COA, COO, Drug Master Files, and Regulatory Support Files are available
Specifications

Specifications

10 mg/mL
Dry Ice
TrueCut™
Cas9 Protein
Genome Editing
SDS
Product Certifications
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