CTSL1 Monoclonal Antibody (OTI2H2), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA809346

Catalog No. 50-168-2730

Description

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: CTSL1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P07711
• Gene Symbols: CTSL
• Immunogen: Full length human recombit protein of human CTSL1 produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2H2
• Conjugate: Unconjugated
• Gene: CTSL
• Gene Alias: CATL, CTSL1, MEP
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1514
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid