CTSL1 Mouse anti-Human, Clone: OTI5C8, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF812846

Catalog No. 50-167-1031

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.

Specifications

• Antigen: CTSL1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CTSL
• Gene Alias: CATL, CTSL1, MEP
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1514
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI5C8
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P07711
• Gene Symbols: CTSL
• Immunogen: Human recombit protein fragment corresponding to amino acids 114-333 of human CTSL produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1