Invitrogen™ CTU1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562843

Catalog No. PIPA562843

Description

Immunogen sequence: RLGISLQLVA VDEGIGGYRD AALAAVRRQA ARWELPLTVV AYEDLFGGWT MDAVARSTAG SGRSRSCCTF CGVLR Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.

Specifications

• Antigen: CTU1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CTU1
• Gene Alias: ATP binding domain 3; Atpbd3; ATP-binding domain-containing protein 3; BC005752; Cancer-associated gene protein; cancer-associated protein; CTU1; Cytoplasmic tRNA 2-thiolation protein 1; cytoplasmic tRNA adenylyltransferase 1; cytosolic thiouridylase subunit 1; cytosolic thiouridylase subunit 1 homolog; cytosolic thiouridylase subunit 1 homolog (S. pombe); NCS6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 90353
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q7Z7A3
• Gene Symbols: CTU1
• Immunogen: Recombinant protein corresponding to Human CTU1. Recombinant protein control fragment (Product #RP-99105).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG