CTXB/beta subunit Cholera Toxin Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-2424	100 μL

Catalog No. 50-198-2424 Supplier Bioss Supplier No. BS12862R

Description

Rabbit Polyclonal Antibody

Cholera toxin (sometimes abbreviated to CTX, Ctx, or CT) is a protein complex secreted by the bacterium Vibrio cholerae. CTX is the causative agent of cholera infection. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit.

Specifications

• Antigen: CTXB/beta subunit Cholera Toxin
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Alias: CTB; CTX; VC1456
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from CTXB/beta subunit Cholera Toxin.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG