Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA523265

Invitrogen™ CUEDC2 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA523265
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA523265 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA523265 Supplier Invitrogen™ Supplier No. PA523265
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

The amino acid sequence used as immunogen is 83% homologous in Porcine and Xenopus.

The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, approximately 40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC2 (CUE domain-containing protein 2) was found through a yeast two-hybrid screening as a protein that interacts with the progesterone receptor (PR) and promotes progesterone-induced PR degradation by the ubiquitin-proteasome pathway. CUEDC2 also decreases the sumoylation of PR. CUEDC2 has also been found to interact with IKK-alpha and IKK-beta and decrease the activation of NF-kappa-B by decreasing the activation of IKK.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CUEDC2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene CUEDC2
Gene Accession No. Q3ZBN4, Q9CXX9, Q9H467
Gene Alias 3010002G01Rik; bA18I14.5; C10orf66; CUE domain containing 2; CUE domain-containing protein 2; CUEDC2; HOYS6; Unknown (protein for MGC:128745)
Gene Symbols CUEDC2
Host Species Rabbit
Immunogen A portion of amino acid 250-287 of human CUEDC2.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100059986, 100738499, 100855631, 516091, 67116, 79004
Target Species Human, Mouse, Canine, Monkey, Bovine, Pig, Horse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.