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Cul2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501572550
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50-157-2550 10 μL
50-157-2549 100 μL
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Catalog No. 50-157-2550 Supplier Bethyl Laboratories, Inc Supplier No. IHC00692T
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, Dog, Horse, Guinea pig_10141, Panda, Orangutan, Monkey, Gorilla, Chimpanzee,

CUL-2 is a member of the family of human cullin genes (CUL-1, -2, -3, -4a, -4b, and -5), homologous to the S. cerevisiae cdc53 gene. CUL-1 forms a complex with human p19skp1 and F box protein p45skp2. Together with cdc53 (Known as CulA), as three subunits, they form a ubiquitin ligase controlling proteolysis of G1 cell cycle regulatory proteins. In contrast to CUL-1, CUL-2 does not associate with p19skp1 and p45skp2. Instead, CUL-2 forms a complex with an inactive transcriptional elongation complex, SIII, formed by three subunits: Elongain C, Elongin B and VHL. The function of this association remains unknown.

Specifications

Antigen Cul2
Applications Immunohistochemistry
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene CUL2
Gene Accession No. Q13617, Q9D4H8
Gene Alias CUL-2
Gene Symbols CUL2
Host Species Rabbit
Immunogen Between 150 and 200
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 71745, 8453
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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