Invitrogen™ Cullin 3 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142413

Catalog No. PIPA5142413

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:2,000.

Cullin 3 is a member of the family of human cullin genes (CUL 1, 2, 3, 4a, 4b, and 5) homologous to the S. cerevisiae cdc 53 gene. CUL 1 forms a complex with human p19 skp1 and F box protein p45 skp2. Together with cdc 53 (Known as Cul A), as three subunits, they form a ubiquitin ligase-controlling proteolysis of G1 cell cycle regulatory proteins. In contrast to CUL 1, CUL 2 does not associate with p19 skp1 and p45 skp2. Instead, CUL 2 forms a complex with an inactive transcriptional elongation complex, SIII, formed by three subunits: Elongain C, Elongin B and VHL. The function of this association remains unknown.

Specifications

• Antigen: Cullin 3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CUL3
• Gene Alias: AI467304; AW146203; Cul3; CUL-3; cullin 3; cullin-3; KIAA0617; mKIAA0617; OTTHUMP00000203839; OTTHUMP00000203840; PHA2E
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 8452
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q13618
• Gene Symbols: CUL3
• Immunogen: Peptide with sequence C-AQVTGSNTRKHILQ (aa 580-593).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG