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Invitrogen™ Cullin 3 Polyclonal Antibody
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Catalog No. PIPA521511
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100 μL
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PIPA521511 100 μL
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Catalog No. PIPA521511 Supplier Invitrogen™ Supplier No. PA521511
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: human CUL3-transfected 293T cells. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (98%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Cullin 3 is a member of the family of human cullin genes (CUL 1, 2, 3, 4a, 4b, and 5) homologous to the S. cerevisiae cdc 53 gene. CUL 1 forms a complex with human p19 skp1 and F box protein p45 skp2. Together with cdc 53 (Known as Cul A), as three subunits, they form a ubiquitin ligase-controlling proteolysis of G1 cell cycle regulatory proteins. In contrast to CUL 1, CUL 2 does not associate with p19 skp1 and p45 skp2. Instead, CUL 2 forms a complex with an inactive transcriptional elongation complex, SIII, formed by three subunits: Elongain C, Elongin B and VHL. The function of this association remains unknown.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cullin 3
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene CUL3
Gene Accession No. Q13618, Q9JLV5
Gene Alias AI467304; AW146203; Cul3; CUL-3; cullin 3; cullin-3; KIAA0617; mKIAA0617; OTTHUMP00000203839; OTTHUMP00000203840; PHA2E
Gene Symbols CUL3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Cullin 3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26554, 8452
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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