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Invitrogen™ Cullin 5 Polyclonal Antibody
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Catalog No. PIPA5102750
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PIPA5102750 100 μL
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Catalog No. PIPA5102750 Supplier Invitrogen™ Supplier No. PA5102750
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CUL5.

CUL5 is a core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. It seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein and may form a cell surface vasopressin receptor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cullin 5
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CUL5
Gene Accession No. Q93034, Q9D5V5, Q9JJ31
Gene Alias 4921514I20Rik; 8430423K24Rik; AI852817; C030032G03Rik; C330021I08Rik; CUL5; CUL-5; cullin 5; cullin-5; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1); Vacm1; VACM-1; vasopressin-activated calcium-mobilizing receptor 1; vasopressin-activated calcium-mobilizing receptor protein; Vasopressin-activated calcium-mobilizing receptor-1
Gene Symbols CUL5
Host Species Rabbit
Immunogen A synthesized peptide derived from human CUL5(Accession Q93034), corresponding to amino acid residues A375-L425.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64624, 75717, 8065
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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