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Cullin 5 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980655
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50-198-0655 100 μL
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Catalog No. 50-198-0655 Supplier Bioss Supplier No. BS10059R
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Description

Rabbit Polyclonal Antibody

CUL5 is a core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAk2. It seems to be involved poteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein and may form a cell surface vasopressin receptor.

Specifications

Antigen Cullin 5
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene CUL5
Gene Accession No. Q93034
Gene Alias 4921514I20Rik; 8430423K24Rik; AI852817; C030032G03Rik; C330021I08Rik; Cul5; CUL-5; cullin 5; Cullin-5; Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1); VACM1; VACM-1; Vasopressin-activated calcium-mobilizing receptor 1; vasopressin-activated calcium-mobilizing receptor protein; Vasopressin-activated calcium-mobilizing receptor-1
Gene Symbols CUL5
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Cullin 5.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8065
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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