Cutaneous Lymphocyte Antigen Rat anti-Human, FITC, Clone: HECA-452, BD

Rat Monoclonal Antibody

Supplier:  BD Biosciences 555947

Catalog No. BDB555947

Description

Reacts with cutaneous lymphocyte associated antigen (CLA), a carbohydrate domain shared by sialyl Lewis[x] (sLe[x]) and sialyl Lewis[a] (sLe[a]) antigens. It serves as the ligand for selectins including CD62E (ELAM-1) and CD62L (LECAM-1). CLA is expressed on lymphocytes in the skin on high endothelium. In peripheral blood, it is expressed on a small subset of lympocytes and all monocytes and granulocytes. It has been suggested that CLA plays a role in supporting lymphocyte migration to extravascular tissue during inflammation. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: HECA-452
Isotype: IgM, κ
Species Reactivity: Human

Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)

Specifications

• Antigen: Cutaneous Lymphocyte Antigen
• Classification: Monoclonal
• Conjugate: FITC
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Lymphocyte-depleted Stromal Preparation of Tonsil
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human, Mouse
• Isotype: IgM κ

• Applications: Flow Cytometry
• Clone: HECA-452
• Description: CLA; PSGL-1; CD162; P-selectin glycoprotein ligand 1; SELPL; SELPLG
• Host Species: Rat
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only.