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Invitrogen™ CWC22 Polyclonal Antibody
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Catalog No. PIPA524276
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400 μL
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Catalog No. Quantity
PIPA524276 400 μL
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Catalog No. PIPA524276 Supplier Invitrogen™ Supplier No. PA524276
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Description

Rabbit Polyclonal Antibody

CWC22 Polyclonal Antibody for Western Blot, IHC (P), Flow

Required for pre-mRNA splicing as component of the spliceosome (PubMed:12226669, PubMed:11991638, PubMed:22961380, PubMed:28502770, PubMed:28076346, PubMed:29360106, PubMed:29301961). Promotes exon-junction complex (EJC) assembly (PubMed:22959432, PubMed:22961380). Hinders EIF4A3 from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs. Through its role in EJC assembly, required for nonsense-mediated mRNA decay. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen CWC22
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene CWC22
Gene Accession No. Q9HCG8
Gene Alias AA684037; AI173004; AL022752; B230213M24; Cwc22; CWC22 homolog, spliceosome-associated protein; CWC22 spliceosome-associated protein; CWC22 spliceosome-associated protein homolog; CWC22 spliceosome-associated protein homolog (S. cerevisiae); EIF4GL; fSAPb; functional spliceosome-associated protein b; KIAA1604; mKIAA1604; NCM; Nucampholin homolog; pre-mRNA-splicing factor CWC22 homolog; RGD1565385
Gene Symbols CWC22
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human CWC22.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 57703
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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