Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA557859

Invitrogen™ CWF19L1 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA557859
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA557859 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA557859 Supplier Invitrogen™ Supplier No. PA557859
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Immunogen sequence: KDVSSLRMML CTTSQFKGVD ILLTSPWPKC VGNFGNSSGE VDTKKCGSAL VSSLATGLKP RYHFAALEKT YYERLPYRNH IILQENAQHA TRF Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%.

CWF19L1 (CWF19 Like Cell Cycle Control Factor 1) is a gene located on chromosome 10 and encodes a protein involved in the regulation of mRNA splicing and cell cycle control. The protein interacts with key splicing factors within the nucleus, including components of the U5 small nuclear ribonucleoprotein (snRNP) and the pre-mRNA processing factor 19 (PRPF19) complex. CWF19L1 plays a crucial role in the alternative splicing of immune-related genes, thereby influencing the expression levels of cytotoxic molecules and enhancing T-cell cytotoxicity. Pathogenic variants in CWF19L1 have been linked to a rare autosomal recessive form of hereditary ataxia known as SCAR17 (Spinocerebellar Ataxia, Autosomal Recessive 17), characterized by symptoms such as global developmental delay, cerebellar ataxia, pyramidal signs, and seizures. This gene's deficiency disrupts normal mRNA splicing and leads to significant alterations in gene expression, impacting cellular and neurological functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CWF19L1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CWF19L1
Gene Accession No. Q69YN2
Gene Alias 2610528C06Rik; AI854304; AV336991; C19L1; Cwf19l1; CWF19-like 1 cell cycle control; CWF19-like 1, cell cycle control (S. pombe); CWF19-like protein 1; hDrn1; SCAR17
Gene Symbols CWF19L1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CWF19L1. Recombinant protein control fragment (Product #RP-97026).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55280
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.