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  5. R&D Systems™ CX08005

R&D Systems™ CX08005
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Catalog No. 61445 Shop All Novus Products
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Catalog No. Quantity
61-445 5 mg
61-442-5 25 mg
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Catalog No. 61-445 Supplier R&D Systems™ Supplier No. 6144/5

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Description

A Tocris product, part of R&D Systems. Competitive PTP1B inhibitor

CX08005 is a competitive PTP1B inhibitor (IC50 = 0.781 μM). Binds catalytic P-loop of enzyme. Improves insulin sensitivity in obese mice in the glucose tolerance test and the homeostasis model assessment of insulin resistance index (HOMA-IR) . Enhances insulin-induced glucose uptake in adipocytes and myotubes in vitro. Exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP.

Specifications

Chemical Name or Material 2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid
CAS 1256341-22-6
Quantity 5 mg
Product Line Tocris
Molecular Formula C28H39N04
Purity 98%
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