Invitrogen™ CX3CL1 Monoclonal Antibody (4C5)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA1031	Invitrogen™ MA1031	100 μg
PIMA1031X	Invitrogen™ MA1031X	20 μL

Description

CX3CL1 Monoclonal Antibody for Western Blot, ELISA

Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.

Specifications

• Antigen: CX3CL1
• Concentration: 1 mg/mL
• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
• Gene Accession No.: O35188, P78423
• Gene ID (Entrez): 20312, 6376
• Immunogen: Non-glycosylated, polypeptide chain containing 76 amino acids of chemokine domain expressed in E. coli.
• Product Type: Antibody

• Clone: 4C5
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse
• Gene: Cx3cl1
• Gene Alias: A-152E5.2; AB030188; ABCD-3; Acc1; AI848747; C3Xkine; chemokine (C-X3-C motif) ligand 1; CX3C; CX3C membrane-anchored chemokine; C-X3-C motif chemokine 1; C-X3-C motif chemokine ligand 1; Cx3cl1; CXC3; CXC3C; D8Bwg0439e; Fkn; Fractalkine; neurotactin; NTN; NTT; Processed fractalkine; SCYD1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D, 1; small-inducible cytokine D1
• Gene Symbols: Cx3cl1
• Primary or Secondary: Primary
• Purification Method: Protein G