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CX3CR1 Mouse, anti-Human, R718, Clone: 2A9-1, BD OptiBuild™

Catalog No. BDB752200 Shop All BD Biosciences Products
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BDB752200 50 μg
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Catalog No. BDB752200 Supplier BD Biosciences Supplier No. 752200
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Description

Mouse Monoclonal Antibody

The 2A9-1 monoclonal antibody specifically binds to human CX3CR1, which is also known as chemokine (C-C) receptor-like 1 (CCRL1), Beta chemokine receptor-like 1 (CMK-BRL-1), G protein-coupled receptor 13 (GPR13), or GPRV28 (V28). CX3CR1 is a seven transmembrane G protein coupled receptor that is expressed by NK cells, T cells, and monocytes. The cellular expression of CX3CR1 is correlated with high levels of intracellular perforin and granzyme B. CX3CR1 serves as a receptor for fractalkine (CX3CL1). Fractalkine is a transmembrane chemokine of the CX3C family that is expressed on activated endothelial cells, neurons, and astrocytes. Interaction of CX3CR1 with fractalkine initiates cellular adhesive and chemotactic responses.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CX3CR1
Applications Flow Cytometry
Classification Monoclonal
Clone 2A9-1
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
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