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Invitrogen™ CX3CR1 Polyclonal Antibody
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Catalog No. PIPA519910
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100 μg
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Catalog No. Quantity
PIPA519910 100 μg
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Catalog No. PIPA519910 Supplier Invitrogen™ Supplier No. PA519910
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Description

Rabbit Polyclonal Antibody

In Western blot applications, this antibody detects a band at ~50kDa. A suggested positive control is human spleen tissue lysate. PA5-19910 can be used with blocking peptide PEP-0036.

CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration an d adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CX3CR1
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CX3CR1
Gene Accession No. P49238
Gene Alias Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKBRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; Cx3c; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; Cx3cr1; Fractalkine receptor; G protein-coupled receptor 13; GPR13; G-protein coupled receptor 13; GPRV28; RBS11; Scyd1; V28
Gene Symbols CX3CR1
Host Species Rabbit
Immunogen Peptide corresponding to 20 amino acids near the amino terminus of mature human CX3CR1. The immunogen is located within the first 50 amino acids of CX3CR1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1524
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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