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Invitrogen™ CX3CR1 Recombinant Rabbit Monoclonal Antibody (1H14L7)

Catalog No. PI702321
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100 μg
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Catalog No. Quantity
PI702321 100 μg
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Catalog No. PI702321 Supplier Invitrogen™ Supplier No. 702321
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Dog, Cat Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration an d adhesion. CX3CR1 is expressed in a variety of human tissues and cell lines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CX3CR1
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 1H14L7
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene CX3CR1
Gene Accession No. P35411, P49238, Q9Z0D9
Gene Alias Beta chemokine receptor-like 1; CCRL1; chemokine (C-C) receptor-like 1; chemokine (C-X3-C motif) receptor 1; chemokine (C-X3-C) receptor 1; CMKBRL1; CMK-BRL1; CMK-BRL-1; CMKDR1; Cx3c; CX3C chemokine receptor 1; C-X3-C CKR-1; C-X3-C motif chemokine receptor 1; Cx3cr1; Fractalkine receptor; G protein-coupled receptor 13; GPR13; G-protein coupled receptor 13; GPRV28; RBS11; Scyd1; V28
Gene Symbols CX3CR1
Host Species Rabbit
Immunogen Peptides corresponding to human CX3CR1 (aa6-19, 339-351).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13051, 1524, 171056
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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