Invitrogen™ CXCL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596432

Catalog No. PIPA596432

Description

Positive Samples: DU145 Immunogen sequence: MARAALSAAP SNPRLLRVAL LLLLLVAAGR RAAGASVATE LRCQCLQTLQ GIHPKNIQSV NVKSPGPHCA QTEVIATLKN GRKACLNPAS PIVKKIIEKM LNSDKSN.

CXCL1, CXCL2, and CXCL3, also known respectively as GRO alpha, GRO beta (MIP-2 alpha) and GRO gamma (MIP-2 beta), are members of the CXC subfamily of chemokines. Mature CXCL1/2/3 proteins bind with high affinity to the IL-8 receptor type B and are potent neutrophil attractants and activators. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.

Specifications

• Antigen: CXCL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cxcl1
• Gene Alias: alpha-chemokine; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); Cinc1; CINC-1; CXC; CXC motif chemokine; C-X-C motif chemokine 1; C-X-C motif chemokine ligand 1; CXCL; CXCL1; CXCL-1; Cytokine-induced neutrophil chemoattractant 1; fibroblast secretory protein; Fsp; Gro; GRO a; GRO a; Gro1; GRO1 oncogene; GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); GROa; GROalpha; GRO-alpha(1-73); GRO-alpha(4-73); GRO-alpha(5-73); GRO-alpha(6-73); Growth-regulated alpha protein; GROa; Hematopoietic synergistic factor; HSF; KC; KC(5-72); KC/GR)-alpha; KC/GRO-alpha; KC-T; melanoma growth stimulating activity, alpha; Melanoma growth stimulatory activity; melanoma growth stimulatory activity alpha; MGSA; MGSA alpha; MGSA-a; N51; NAP3; NAP-3; Neutrophil-activating protein 3; platelet-derived growth factor-inducible protein KC; SCYB1; secretory protein N51
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2919, 81503
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.22 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P09341, P14095
• Gene Symbols: Cxcl1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-107 of human GRO alpha (NP_0015021).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov