Invitrogen™ CXCL11 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547767

Catalog No. PIPA547767

Description

In sandwich ELISAs, less than 0.2% cross-reactivity with recombinant human CXCL11, recombinant mouse (rm) BLC, rmCRG-2, rmGCP-2, rmMIG, rmPF4, and rmSDF-1 alpha is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.

Interferon-inducible T-cell alpha chemoattractant ( I-TAC), belonging to the CXC chemokine family, is expressed in peripheral blood leukocytes, pancreas and liver, thymus, spleen, lung, small intestine, placenta and prostate. Its molecular weight is 8-11 kD. I-TAC is also known as CXCL-11 and IP-9. The cytokine is involved in regulating calcium release and inducing a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. It is upregulated in patients with AIDS, dementia and in patients with multiple sclerosis.

Specifications

• Antigen: CXCL11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CXCL11
• Gene Alias: betaR1; beta-R1; b-R1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 11; CXC; CXC motif chemokine; C-X-C motif chemokine 11; C-X-C motif chemokine ligand 11; Cxc11; CXCL; CXCL11; H174; Interferon gamma-inducible protein 9; interferon-inducible T-cell alpha chemoattractant; IP9; IP-9; Itac; I-TAC; MGC102770; Scyb11; Scyb9b; small inducible cytokine B11; small inducible cytokine subfamily B (Cys-X-Cys), member 11; small inducible cytokine subfamily B (Cys-X-Cys), member 9B; small-inducible cytokine B11
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56066
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: ELISA, Neutralization, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q9JHH5
• Gene Symbols: CXCL11
• Immunogen: E. coli-derived recombinant mouse CXCL11/I-TAC Phe22-Met100.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG