CXCL12 alpha (SDF-1 alpha) Polyclonal Antibody, PeproTech®, Invitrogen™

Goat Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
500P164G50	Invitrogen™ 500P164G50UG	50 μg
500P164G100	Invitrogen™ 500P164G100UG	100 μg

Description

AA Sequence of recombinant protein: KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK. Preparation: Produced from sera of goats immunized with highly pure recombinant Murine SDF-1alpha (CXCL12). Anti-Murine SDF-1alpha (CXCL12)-specific antibody was purified by affinity chromatography employing an immobilized Murine SDF-1alpha (CXCL12) matrix. Sandwich ELISA: To detect Murine SDF-1alpha (CXCL12) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Murine SDF-1alpha (CXCL12) (500-P164GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Murine SDF-1alpha (CXCL12). Western Blot: To detect Murine SDF-1alpha (CXC12) by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. When used in conjunction with compatible secondary reagents, the detection limit for Recombinant Murine SDF-1alpha (CXCL12) is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

CXCL12 is a stromal cell-derived alpha chemokine member of the intercrine family. This gene product and its receptor CXCR4 can activate lymphocytes and have been implicated in the metastasis of some cancers such as breast cancer. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CXCL12 alpha (SDF-1 alpha)
• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Host Species: Goat
• Target Species: Mouse
• Gene Accession No.: P40224
• Gene ID (Entrez): 20315
• Immunogen: E.coli-derived Recombinant Murine SDF-1alpha (CXCL12).
• Purification Method: Antigen Affinity Chromatography
• Gene: CXCL12

• Concentration: 0.1-1.0 mg/mL
• Classification: Polyclonal
• Form: Lyophilized
• Regulatory Status: RUO
• Formulation: PBS with no preservative
• Gene Alias: 12-O-tetradecanoylphorbol 13-acetate repressed protein 1; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 12; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); CXC; CXC motif chemokine; C-X-C motif chemokine 12; C-X-C motif chemokine ligand 12; CXCL; Cxcl12; H-SDF-1-alpha; Intercrine reduced in hepatomas; IRH; Pbsf; pre-B cell growth-stimulating factor; pre-B-cell growth-stimulating factor; SCYB12; SDF 1 a; SDF 1 alpha; SDF 1a; SDF1; SDF-1; SDF1 alpha; SDF-1 gamma; SDF1A; SDF-1-alpha(3-67); SDF1B; SDF-1-beta(3-72); SDF1a; Stromal cell-derived factor 1; stromal cell-derived factor-1 alpha; stromal cell-derived factor-1 gamma; thymic lymphoma cell-stimulating factor; TLSF; Tpar1
• Gene Symbols: CXCL12
• Primary or Secondary: Primary
• Content And Storage: -20°C