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CXCL17 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5122056

Encompass

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Catalog No. PIPA5122056


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Description

Description

CXCL17 is a chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. In particular, CXCL17 is a mucosal chemokine that attracts dendritic cells and blood monocytes to the lungs. CXCL17 plays a role in angiogenesis and possibly in the development of tumors. Further, CXCL17 acts as an anti-inflammatory in the stomach and may play a role in the innate defense against infections. CXCL17 also activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17 seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. Diseases associated with CXCL17 dysfunction include cholera.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CXCL17
Polyclonal
Unconjugated
CXCL17
13.6 kDa protein; 13.6-kDa protein; 4-Cys CXCL17; 6-Cys CXCL17; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 17; CXC; CXC motif chemokine; C-X-C motif chemokine 17; C-X-C motif chemokine ligand 17; CXCL; CXCL17; Dcip1; Dendritic cell and monocyte chemokine-like protein; DMC; UNQ473; UNQ473/PRO842; Vcc1; VCC-1; VEGF coregulated chemokine 1; VEGF co-regulated chemokine 1
Rabbit
Antigen affinity chromatography
RUO
284340
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.55 mg/mL
PBS with 50% glycerol and 0.05% ProClin 300
Q6UXB2
CXCL17
Leu24-Leu119 (Accession Q6UXB2), with N-terminal His and GST Tag
100 μL
Primary
Human
Antibody
IgG
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