Invitrogen™ CXCL17 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5122056

Catalog No. PIPA5122056

Description

CXCL17 is a chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. In particular, CXCL17 is a mucosal chemokine that attracts dendritic cells and blood monocytes to the lungs. CXCL17 plays a role in angiogenesis and possibly in the development of tumors. Further, CXCL17 acts as an anti-inflammatory in the stomach and may play a role in the innate defense against infections. CXCL17 also activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17 seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. Diseases associated with CXCL17 dysfunction include cholera.

Specifications

• Antigen: CXCL17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CXCL17
• Gene Alias: 13.6 kDa protein; 13.6-kDa protein; 4-Cys CXCL17; 6-Cys CXCL17; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 17; CXC; CXC motif chemokine; C-X-C motif chemokine 17; C-X-C motif chemokine ligand 17; CXCL; CXCL17; Dcip1; Dendritic cell and monocyte chemokine-like protein; DMC; UNQ473; UNQ473/PRO842; Vcc1; VCC-1; VEGF coregulated chemokine 1; VEGF co-regulated chemokine 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 284340
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.55 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q6UXB2
• Gene Symbols: CXCL17
• Immunogen: Leu24-Leu119 (Accession Q6UXB2), with N-terminal His and GST Tag.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG