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Invitrogen™ CXCL17 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA5122057
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100 μL
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PIPA5122057 20 μL
PIPA5122056 100 μL
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Catalog No. PIPA5122057 Supplier Invitrogen™ Supplier No. PA5122057
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Description

Rabbit Polyclonal Antibody

CXCL17 is a chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. In particular, CXCL17 is a mucosal chemokine that attracts dendritic cells and blood monocytes to the lungs. CXCL17 plays a role in angiogenesis and possibly in the development of tumors. Further, CXCL17 acts as an anti-inflammatory in the stomach and may play a role in the innate defense against infections. CXCL17 also activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions. 4-Cys CXCL17 seems to exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17. Diseases associated with CXCL17 dysfunction include cholera.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CXCL17
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene CXCL17
Gene Accession No. Q6UXB2
Gene Alias 13.6 kDa protein; 13.6-kDa protein; 4-Cys CXCL17; 6-Cys CXCL17; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 17; CXC; CXC motif chemokine; C-X-C motif chemokine 17; C-X-C motif chemokine ligand 17; CXCL; CXCL17; Dcip1; Dendritic cell and monocyte chemokine-like protein; DMC; UNQ473; UNQ473/PRO842; Vcc1; VCC-1; VEGF coregulated chemokine 1; VEGF co-regulated chemokine 1
Gene Symbols CXCL17
Host Species Rabbit
Immunogen Leu24-Leu119 (Accession Q6UXB2), with N-terminal His and GST Tag.
Purification Method Antigen affinity chromatography, Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 284340
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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