Invitrogen™ CXCL6 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 500P120BT500UG

Catalog No. 50-271-8694

Description

AA Sequence of recombinant protein: VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human GCP-2 (CXCL6). Anti-Human GCP-2 (CXCL6)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Human GCP-2 (CXCL6) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human GCP-2 (CXCL6) (500-P120) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human GCP-2 (CXCL6). Western Blot: To detect hGCP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hGCP-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P120BT-1MG will be provided as 2 x 500 μg

CXCL6 is a chemotactic for neutrophil granulocytes. It signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).

Specifications

• Antigen: CXCL6
• Classification: Polyclonal
• Conjugate: Biotin
• Gene: CXCL6
• Gene Alias: C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 5; chemokine (C-X-C motif) ligand 6; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); chemokine alpha 3; CKA3; CKA-3; CXC; CXC chemokine LIX; CXC motif chemokine; C-X-C motif chemokine 5; C-X-C motif chemokine 6; C-X-C motif chemokine ligand 6; CXCL; Cxcl5; CXCL6; Cytokine LIX; GCP2; GCP-2; granulocyte chemotactic protein 2; Scyb5; SCYB6; small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2); Small inducible cytokine subfamily B (Cys-X-Cys), member b; small-inducible cytokine B5; Small-inducible cytokine B6; Small-inducible cytokine B6, N-processed variant 1; Small-inducible cytokine B6, N-processed variant 2; Small-inducible cytokine B6, N-processed variant 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6372
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Western Blot
• Concentration: 0.1-1.0 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P80162
• Gene Symbols: CXCL6
• Immunogen: E.coli-derived Recombinant Human GCP-2 (CXCL6).
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG