Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA548299

Invitrogen™ CXCR1 Chimeric Recombinant Rabbit Monoclonal Antibody (SE2)
GREENER_CHOICE

Catalog No. PIMA548299
Change view
Click to view available options
Quantity:
200 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA548299 200 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIMA548299 Supplier Invitrogen™ Supplier No. MA548299
Add to Cart
Add to Cart

Description

Rabbit Recombinant Monoclonal Antibody

Specificity: SE2 antibody is specific for IL-8RA and does not corss-react with IL-8RB. IL-8RA is a receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils.

CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CXCR1 Chimeric
Applications Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone SE2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene CXCR1
Gene Accession No. P25024
Gene Alias C Cmotif chemokine; C X C motif chemokine; C-C; CC motif chemokine; C-C-CKR-1; CCmotif chemokine; CD128; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; CXC; CXC chemokine receptor 1; C-X-C chemokine receptor type 1; CXC motif chemokine; C-X-C motif chemokine receptor 1; CXCR1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL8R1; Il8ra; IL8RBA; IL-RA; interleukin 8 receptor; interleukin 8 receptor alpha; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
Gene Symbols CXCR1
Host Species Rabbit
Immunogen This antibody was raised by immunizing BALB/c mice with a BSA-conjugated peptide comprising of the N-terminal part of IL-8RA (amino acids 1-30).
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3577
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.