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CXCR2 (extracellular) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA5111765
Description
Reconstitute antibody with 50 μL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). Peptide sequence is: (C)EDFNMES DSFEDFWKGE D Homology: Human only.
CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to GRO/MGSA and NAP-2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
Specifications
CXCR2 (extracellular) | |
Polyclonal | |
Unconjugated | |
CXCR2 | |
C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD128; CD182; CD182 antigen; CDw128; CDw128b; Cmkar2; CXC; C-X-C chemokine receptor type 2; CXC motif chemokine; Cxcr2; CXC-R2; Gpcr16; GRO/MGSA receptor; High affinity interleukin-8 receptor B; Il-8 receptor b; IL-8 receptor beta; IL-8 receptor type 2; IL-8R B; IL8R2; IL8RA; IL8RB; IL-8rb; IL-8Rh; mIL-8RH | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
3579 | |
-20°C | |
Lyophilized |
Flow Cytometry, Western Blot | |
0.55 mg/mL | |
PBS with 1% BSA and 0.05% sodium azide; pH 7.4 | |
P25025 | |
CXCR2 | |
Peptide corresponding to amino acid residues 2-19 of human CXCR2 (Extracellular, N-terminus) | |
50 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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