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Invitrogen™ CXCR2 Monoclonal Antibody (GT547)
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Catalog No. PIMA531520
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100 μL
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Catalog No. Quantity
PIMA531520 100 μL
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Catalog No. PIMA531520 Supplier Invitrogen™ Supplier No. MA531520
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Description

Mouse Monoclonal Antibody

Keep as concentrated solution. Predicted reactivity: Chimpanzee (100%). Positive Control: 3xFlag-human CXCR2-transfected 293T. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to GRO/MGSA and NAP-2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CXCR2
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone GT547
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and no preservative; pH 7
Gene CXCR2
Gene Accession No. P25025
Gene Alias C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD128; CD182; CD182 antigen; CDw128; CDw128b; chemokine (C-X-C motif) receptor 2; chemokine (CXC) receptor 2; chemokine (C-X-C) receptor 2; Cmkar2; CXC; C-X-C chemokine receptor type 2; CXC motif chemokine; C-X-C motif chemokine receptor 2; Cxcr2; CXC-R2; CXCR-2; CXCR2 gene for IL8 receptor type B; Gpcr16; GRO/MGSA receptor; high affinity interleukin-8 receptor B; IL-8 receptor alpha chain; Il-8 receptor b; IL-8 receptor beta; IL-8 receptor type 2; IL-8R B; IL8R2; IL8RA; Il8rb; IL-8rb; IL-8Rh; interleukin 8 receptor B; interleukin 8 receptor type 2; interleukin 8 receptor, beta; interleukin-8 receptor type B; mIL-8RH
Gene Symbols CXCR2
Host Species Mouse
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human CXCR2. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3579
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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