CXCR4 Mouse anti-Human, Clone: 12G5, Abnova™

Mouse monoclonal antibody raised against human CXCR4.

Supplier:  Abnova Corporation MAB12537

Catalog No. 89-934-026

Description

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Specifications

• Antigen: CXCR4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry Immunofluorescence Immunohistochemistry (Frozen sections) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) The optimal working dilution should be determined by the end user.
• Gene Alias: CD184/D2S201E/FB22/HM89/HSY3RR/LAP3/LCR1/LESTR/NPY3R/NPYR/NPYRL/NPYY3R/WHIM
• Host Species: Mouse
• Purification Method: Affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 7852
• Content And Storage: Store at 4°C. Do not freeze.
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (PFA fixed)
• Clone: 12G5
• Description: Mouse monoclonal antibody raised against human CXCR4.
• Formulation: In PBS, pH 7.2 (0.09% sodium azide).
• Gene Symbols: CXCR4
• Immunogen: cP-MAC-infected Sup-T1 cells
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid