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Description
The monoclonal antibody 2G8 reacts with the mouse CXC chemokine receptor, CXCR5. CXCR5 (a.k.a. BLR1, NLR and MDR15), a seven-transmembrane, G-protein-coupled receptor, is the specific receptor for CXC chemokines, CXCL13/BLC/BCA-1. The expression of CXCR5 has been detected in spleen, lymph nodes, tonsils, brain, bone marrow, T cells, B cells, cerebrum, cerebellum, hippcampus and pituitary. In mouse spleen, CXCR5 was strictly expressed by mature B cells and a small subset of T lymphocytes. The immunogen used to generate 2G8 hybridoma was a recombinant protein containing N-terminal amino acids of mouse CXCR5 (GST-NmBLR1). This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Host Species: Rat
Clone: 2G8
Isotype: IgG2a κ
Species Reactivity: Mouse
Immunogen: Mouse CXCR5
Flow Cytometry
Specifications
Specifications
| Antigen | CXCR5 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | 2G8 |
| Concentration | 0.2mg/mL |
| Conjugate | PE |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Rat |
| Immunogen | Mouse CXCR5 |
| Purification Method | Affinity Purified |
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For Research Use Only.
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