CXCR6 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA527171

Catalog No. PIPA527171

Description

Recommended positive controls: 293T. Predicted reactivity: Rhesus Monkey (100%), Chimpanzee (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

CD186, also known as CXCR6, is a G protein-coupled chemokine receptor reported to be one of the cellular receptors of HIV and SIV. CD186 is expressed by NKT cells, various subtypes of T cells with activated and memory phenotypes, and some plasma cells. It has been reported that mouse liver NK cells, but not naïve or splenic NK cells, express CD186. The ligand of CD186, CXCL16, is expressed by macrophages, dendritic cells and liver endothelial cells. Being highly expressed on NKT cells, CD186 is often used as a proxy marker of this cell subset.

Specifications

• Antigen: CXCR6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CXCR6
• Gene Alias: BB217514; BONZO; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD186; CD186 antigen; CDw186; chemokine (C-X-C motif) receptor 6; chemokine receptor CXCR6; CXC; C-X-C chemokine receptor type 6; CXC motif chemokine; C-X-C motif chemokine receptor 6; Cxcr6; CXC-R6; CXCR-6; G protein-coupled receptor; G-protein coupled receptor bonzo; G-protein coupled receptor STRL33; OTTHUMP00000209997; OTTHUMP00000209998; STRL33; TYMSTR
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10663
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.42 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O00574
• Gene Symbols: CXCR6
• Immunogen: Synthetic peptide corresponding to a region within amino acids 82 and 172 of Human Bonzo
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG