Invitrogen™ CXXC5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566138

Catalog No. PIPA566138

Description

Immunogen sequence: ASLLANGHDLA AAMAVDKSNP TSKHKSGAVA SLLSKAERAT ELAAEGQLTL QQFAQSTEML KRVVQEHLPL Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.

CXXC5 is zinc finger protein closely related to the DVL1-binding protein CXXC4 (also known as Idax), and like CXXC4 is thought to modulate the Wnt signaling pathway during development. CXXC5 is upregulated in neural stem cells upon BMP4 stimulation, leading to decreased levels of the Wnt-signaling target AXIN2 and facilitated the response of the stem cells to Wnt3a. Recent reports suggest CXXC5 transcription is activated by the Wilms tumor 1 (WT1) transcription factor, and together are involved in the WNT/beta-catenin pathway and play a role in embryonic kidney development.

Specifications

• Antigen: CXXC5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CXXC5
• Gene Alias: 4930415K17Rik; CF5; CXXC finger 5; CXXC finger 5 protein; CXXC finger protein 5; Cxxc5; CXXC-type zinc finger protein 5; HSPC195; Putative MAPK-activating protein PM08; putative NF-kappa-B-activating protein 102; Retinoid-inducible nuclear factor; RINF; TCCCIA00297; WID; WT1-induced Inhibitor of Dishevelled
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51523
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q7LFL8
• Gene Symbols: CXXC5
• Immunogen: Recombinant Human CXXC5. Recombinant protein control fragment (Product #RP-105094).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG